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. 2012 May;31(5):248–256. doi: 10.5732/cjc.011.10383

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Chinese Journal of Cancer

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Figure 4. — A, YC-1 promoted apoptosis in a dose-dependent manner. B, the expression of Caspase 8 increased, but the expression of Caspase 3 and Caspase 9 were not obviously changed after YC-1 treatment. C, YC-1 induced cell cycle arrest at G₁ phase. D, the expression of P21 and P27 increased after YC-1 treatment. *P < 0.05, **P < 0.01, vs. control.