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. Author manuscript; available in PMC: 2014 Jun 1.
Published in final edited form as: Mol Nutr Food Res. 2013 Apr 11;57(6):996–1006. doi: 10.1002/mnfr.201200630

Figure 4.

Figure 4

CFA-mediated upregulation of P2X3 expression in STN neurons is repressed in rats receiving cocoa as a dietary supplement. Sections of spinal cord containing STN were obtained from untreated animals (CON), animals on diets supplemented with 10% cocoa for 14 days (COCOA), animals 7 days post CFA injection (CFA), or animals on a cocoa-enriched diet and injected with CFA 7 days prior to harvesting the spinal cord (COCOA + CFA). (A) Images of the STN stained for P2X3 are shown. (B) The average fold change ± SEM of P2X3 staining intensity when compared to the mean of the control that was made equal to one is reported (n = 3). * p < 0.01 increase when compared to control while # p < 0.01 decrease compared to CFA. Magnification bar = 50 μm.