. Author manuscript; available in PMC: 2014 Jun 1.

Published in final edited form as: Mol Nutr Food Res. 2013 Apr 11;57(6):996–1006. doi: 10.1002/mnfr.201200630

Table 2.

Relative Fold-Change in Cytokine Levels in the Spinal Trigeminal Nucleus in Response to CFA and Cocoa Enriched Diets. The level of all cytokines were significantly (p < 0.05) elevated above control levels.

	Fold-Change From Control
	CFA	COCOA +CFA

CINC-2α/β	2.26 ± 0.86	1.26 ± 0.69^#
IL-1α	2.00 ± 0.56	1.58 ± 0.82^#
IL-1ra	4.69 ± 2.31	3.05 ± 0.80
IL-2	2.33 ± 0.60	2.33 ± 0.73
IL-3	2.58 ± 0.78	2.30 ± 0.44
IL-4	2.20 ± 0.76	1.36 ± 0.44^#
IL-13	2.04 ± 0.46	1.25 ± 0.57^#
IL-17	2.83 ± 0.64	1.61 ± 0.62^#
IP-10	2.72 ± 0.72	3.12 ± 0.83
LIX	2.41 ± 0.68	2.38 ± 0.81
MIG	2.94 ± 1.35	2.30 ± 0.74
RANTES	2.42 ± 0.72	1.83 ± 0.49^#
TNF-α	3.23 ± 1.41	1.75 ± 0.90^#
VEGF	4.27 ±1.71	2.57 ± 0.86^#

designates when p < 0.05 when compared to CFA simulation.