Table II.
Meta-analysis of included data (to 2011): BMI and IVF outcomes in women using donor oocytes.
| BMI category (kg/m2) | Number of studiesa | Sample size | Statistical model | RR (95%CI) | Statistical heterogeneity (I2, %) |
|---|---|---|---|---|---|
| Implantation (n = 4758) | |||||
| <20 | 6 | 791 | Random effects | 1.01 (0.91–1.12) | 0 |
| 20–24.9 | 2665 | – | Reference | ||
| 25–29.9 | 6 | 892 | Random effects | 0.92 (0.822–1.02) | 0 |
| >30 | 6 | 410 | Random effects | 0.93 (0.80–1.07) | 0 |
| Clinical pregnancy (n = 4662) | |||||
| <20 | 5 | 784 | Random effects | 1.03 (0.93–1.15) | 44.8 |
| 20–24.9 | 2613 | – | Reference | ||
| 25–29.9 | 5 | 867 | Random effects | 0.94 (0.88–1.01) | 0 |
| >30 | 5 | 398 | Random effects | 0.98 (0.83–1.15) | 61.6 |
| Miscarriage (n = 4662) | |||||
| <20 | 5 | 784 | Random effects | 0.92 (0.73–1.17) | 0 |
| 20–24.9 | 2613 | – | Reference | ||
| 25–29.9 | 5 | 867 | Random effects | 0.90 (0.59–1.34) | 45.3 |
| >30 | 5 | 398 | Random effects | 1.12 (0.83–1.50) | 0 |
| Live birth (n = 568) | |||||
| <20 | 3 | 24 | Random effects | 0.83 (0.57–1.21) | 0 |
| 20–24.9 | 224 | – | Reference | ||
| 25–29.9 | 3 | 176 | Random effects | 1.02 (0.82–1.25) | 0 |
| >30 | 3 | 144 | Random effects | 0.91 (0.65–1.27) | 47.9 |
RR, risk ratio; CI, confidence intervals.
aData were available for each outcome from the following studies as listed:
Implantation: Wattanakumtornkul et al. (2003); Styne-Gross et al. (2005); Bellver et al. (2007); Bodri et al. (2010); DeUgarte et al. (2010; Washington University IVF center data; Clinical pregnancy and miscarriage: Styne-Gross et al. (2005); Bellver et al. (2007); Bodri et al. (2010); DeUgarte et al. (2010), Washington University IVF center data; Live birth: Wattanakumtornkul et al. (2003); DeUgarte et al. (2010), Washington University IVF center data.