Table 1.
Demographics and Cognitive Performance
| NCI | MCI | AD | |
|---|---|---|---|
|
|
|||
| Number of cases | 7 | 5 | 12 |
| Age at death (y) | 83.35 ± 8.36 | 84.09 ± 9.77 | 89.94 ± 4.04 |
| Education (y) | 19.43 ± 3.60 | 17.00 ± 4.00 | 18.92 ± 2.23 |
| Postmortem Interval (h) | 6.03 ± 2.47 | 6.91 ± 2.04 | 12.03 ± 7.95 |
| Gender | 5 M, 2 F | 3 M, 2 F | 3 M, 9 F |
| Global Cognitive Score | −0.11 ± 0.55** | 0.22 ± 0.24** | −2.07 ± 1.09 |
| MMSE | 27.71 ± 1.80** | 28.19 ± 1.29** | 13.35 ± 9.13 |
| Episodic Memory | 0.06 ± 0.45** | 0.56 ± 0.29** | −2.37 ± 1.18 |
| Semantic Memory | 0.30 ± 0.48* | 0.18 ± 0.47* | −1.80 ± 1.33 |
| Working Memory | −0.43 ± 0.78* | −0.34 ± 0.78* | −1.56 ± 0.90 |
| Visuospatial Ability | −0.36 ± 1.00 | 0.03 ± 0.48 | −1.32 ± 0.84 |
| Perceptual Speed | −0.56 ± 1.04* | 0.34 ± 0.49* | −1.85 ± 0.98 |
Data represent mean ± SD.
F, female; M, male; NCI, non-cognitive impairment; MCI, mild-cognitive impairment; AD, Alzheimer disease; MMSE, Mini-mental state examination.
ANOVA p < 0.0001, Bonferroni Multiple Comparisons post Test
p < 0.01 and
p < 0.001 vs. AD.