Table I.
Patient characteristics and treatment by age
| Variable | Overall (N = 2122) | 65-79 y (n = 1645) | ≥80 y (n = 477) |
|---|---|---|---|
| Demographics | |||
| Median age (y) (25th, 75th) | 74.0 (69.0, 79.0) | 72.0 (68.0, 76.0) | 83.0 (81.0, 85.0) |
| Female sex, n (%) | 918 (43.3) | 667 (40.5) | 251 (52.6) |
| Race, n (%)* | |||
| White | 1760 (83.9) | 1368 (84.0) | 394 (83.7) |
| Black | 265 (12.6) | 200 (12.3) | 65 (13.8) |
| Native American | 55 (2.6) | 44 (2.7) | 11 (2.3) |
| Other | 18 (0.9) | 17 (1.0) | 1 (0.2) |
| Medical history, n (%) | |||
| Hypertension | 1531 (72.1) | 1183 (71.9) | 348 (73.0) |
| Hyperlipidemia | 1109 (52.3) | 871 (52.9) | 238 (49.9) |
| Smoking | 806 (38.0) | 658 (40.0) | 148 (31.0) |
| Diabetes | 529 (24.9) | 433 (26.3) | 96 (20.1) |
| CHF* | 912 (44.0) | 707 (43.9) | 205 (44.2) |
| NYHA class | |||
| I | 39 (1.9) | 28 (1.7) | 11 (2.4) |
| II | 212 (10.2) | 180 (11.2) | 32 (6.9) |
| III | 454 (21.9) | 346 (21.5) | 108 (23.3) |
| IV | 207 (10.0) | 153 (9.5) | 54 (11.6) |
| Median ejection fraction (%) (25th, 75th) | 55.1 (41.7, 64.5) | 56.0 (42.0, 64.7) | 52.9 (40.7, 63.4) |
| MI | 646 (30.4) | 477 (29.0) | 169 (35.4) |
| PCI | 252 (11.9) | 211 (12.8) | 41 (8.6) |
| CABG | 494 (23.3) | 379 (23.0) | 115 (24.1) |
| Cerebrovascular disease | 319 (15.0) | 235 (14.3) | 84 (17.6) |
| Stroke | 85 (4.0) | 64 (3.9) | 21 (4.4) |
| Peripheral vascular disease | 200 (9.4) | 154 (9.4) | 46 (9.6) |
| GI bleed | 85 (4.0) | 61 (3.7) | 24 (5.0) |
| Thyroid disease | 63 (3.0) | 47 (2.9) | 16 (3.4) |
| Presenting clinical characteristics | |||
| Median heart rate (beats/min) (25th, 75th) | 74.0 (63.0, 87.0) | 74.0 (63.0, 87.0) | 73.0 (64.0, 86.0) |
| Median BP (mm Hg) (25th, 75th) | |||
| Systolic | 142.0 (126.0, 160.0) | 141.0 (126.0, 159.0) | 143.0 (129.0, 164.5) |
| Diastolic | 77.0 (67.0, 87.0) | 78.0 (67.0, 88.0) | 77.0 (67.0, 85.0) |
| Median baseline GFR (mL/min) (25th, 75th) | 62.8 (49.7, 76.6) | 63.9 (51.3, 78.2) | 56.5 (46.0, 72.1) |
| Dialysis, n (%) | 38 (1.8) | 34 (2.1) | 4 (0.8) |
| Median hematocrit (%) (25th, 75th) | 38.0 (34.0, 42.0) | 39.0 (35.0, 42.0) | 37.0 (33.0, 41.0) |
| Stable CAD, n (%) | 989 (46.6) | 808 (49.1) | 181 (37.9) |
| Presenting with ACS, n (%) | 1133 (53.4) | 837 (50.9) | 296 (62.1) |
| MI | 383 (18.0) | 263 (16.0) | 121 (25.4) |
| Unstable angina | 750 (35.3) | 574 (34.9) | 175 (36.7) |
| No. of diseased vessels at catheterization, n (%) | |||
| 1 | 466 (22.0) | 363 (22.1) | 103 (21.6) |
| 2 | 350 (16.5) | 254 (15.4) | 96 (20.1) |
| 3 | 573 (27.0) | 425 (25.8) | 148 (31.0) |
| Median CHADS2 score (25th, 75th)* | 2.0 (1.0, 3.0) | 2.0 (1.0, 2.0) | 2.0 (2.0, 3.0) |
| 0, n (%) | 172 (8.3) | 172 (10.7) | 0 (0.0) |
| 1, n (%) | 578 (27.9) | 507 (31.5) | 71 (15.3) |
| ≥2, n (%) | 1324 (63.8) | 931 (57.8) | 393 (84.7) |
| Median ATRIA score (25th, 75th) | 3.0 (1.0, 5.0) | 3.0 (1.0, 4.0) | 5.0 (3.0, 6.0) |
| Low (0-3), n (%) | 1137 (53.6) | 948 (57.6) | 189 (39.6) |
| Intermediate (4), n (%) | 336 (15.8) | 314 (19.1) | 22 (4.6) |
| High (5-10), n (%) | 649 (30.6) | 383 (23.3) | 266 (55.8) |
| Treatment | |||
| PCI, n (%) | 551 (26.0) | 406 (24.7) | 145 (30.4) |
| BMS | 325 (15.3) | 228 (13.9) | 97 (20.3) |
| DES | 189 (8.9) | 146 (8.9) | 43 (9.0) |
| Other | 37 (1.7) | 32 (1.9) | 5 (1.0) |
| CABG, n (%) | 209 (9.8) | 176 (10.7) | 33 (6.9) |
25th, 75th indicates 25th and 75th percentiles, respectively. Abbreviations: CHF, Congestive heart failure; NYHA, New York Heart Association; GI, gastrointestinal; BP, blood pressure; GFR, glomerular filtration rate; BMS, bare-metal stent; DES, drug-eluting stent.
*
n ≠ 2,122 due to missing data.