Table 4.
Comparison | Brain region | Milliliters | X | Y | Z | P-value (corrected) |
---|---|---|---|---|---|---|
Anxiety > NoAnxiety | Medial–posterior cerebellum | 5.6 | 2 | − 68 | − 26 | < 0.001 |
Left culmen | 4.0 | − 28 | − 28 | − 32 | < 0.001 | |
Right inferior MPFC | 2.78 | 18 | 28 | − 20 | < 0.001 | |
Right superior temporal gyrus | 2.17 | 36 | − 4 | − 18 | < 0.001 | |
Right parahippocampal gyrus | 2.03 | 18 | − 28 | − 4 | < 0.001 | |
Right caudate | 1.21 | 12 | 28 | − 2 | < 0.001 | |
Left superior temporal gyrus | 0.92 | − 32 | 6 | − 16 | < 0.005 | |
Depression > NoDepression | Right lingual gyrus Right fusiform gyrus |
5.49 1.10 |
6 − 36 |
− 82 − 60 |
− 16 − 20 |
< 0.001 < 0.005 |
Right vermis | 0.72 | − 10 | − 68 | − 36 | < 0.01 | |
PTSD > NoPTSD | Left declive | 3.14 | − 2 | − 72 | − 12 | < 0.001 |
Left lingual gyrus | 0.84 | − 14 | − 88 | − 2 | < 0.005 |
All coordinates are presented in MNI space.
Anxiety > NoAnxiety, regions in which alcoholics without anxiety demonstrated less gray matter relative to alcoholics with anxiety. Depression > NoDepression — regions in which alcoholics without depression demonstrated less gray matter than alcoholics with depression. PTSD > NoPTSD — regions in which alcoholics without PTSD demonstrated less gray matter than alcoholics with PTSD. There was no gray matter differences in the opposite direction to the above mentioned.