Fig. 7.

The results of the connectometry under different length thresholds. (A) An example of a subject (patient 2) with chronic stroke. The old infarct and lacunar lesions can be observed on the T₂-wieghted images (arrows). (B) The corresponding connectometry of the subject at length thresholds of 10, 20, and 30 (unit in voxel distance). A higher length threshold provides more specific results to confirm the affected tracks, although it may fail to identify all of the possible affected tracks. By contrast, a lower length threshold is more sensitive to potentially affected tracks, although it may include more false positive results due to a higher false discovery rate. The optimal setting depends on the balance between sensitivity and specificity.