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. Author manuscript; available in PMC: 2014 Jun 26.
Published in final edited form as: Vaccine. 2013 Apr 28;31(30):3090–3097. doi: 10.1016/j.vaccine.2013.03.060

Figure 3. Heterogeneity in phenotypes of responding CD4+ T-cells among very young children and adults.

Figure 3

A. PBMC from adults (n=11) and children (n=17) were stimulated with SEB, analyzed by ICS, and cytokine-producing CD4 T cells were divided according to the expression of CD45RA and CCR7. Representative samples from one adult and one child are shown (black dots). B. The percentages of total cytokine-producing cells contributed by each subpopulation after SEB stimulation are shown. C. The percentages of total IL-2-producing cells responding to three bacterial antigens are shown. P values adult vs. young children <0.05.