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. Author manuscript; available in PMC: 2013 Sep 19.
Published in final edited form as: Shock. 2011 Jun;35(6):626–631. doi: 10.1097/SHK.0b013e31820fe671

Table 2. Changes in cardiopulmonary variables.

Time after injury (hours)

0 6 12 18 24 36 48
MAP, mmHg
 Sham 96 ± 3 107 ± 3 103 ± 4 103 ± 2 100 ± 2 97 ± 4 96 ± 3
 Control 96 ± 3 114 ± 6 105 ± 5 103 ± 4 102 ± 5 102 ± 6 104 ± 5
 Treatment 94 ± 4 116 ± 5 113 ± 7 111 ± 5 107 ± 5 103 ± 3 106 ± 5
HR, bpm
 Sham 83 ± 3 92 ± 3 117 ± 10 113 ± 8 107 ± 5 101 ±5 90 ± 3
 Control 91 ± 5 124 ± 10a 118 ± 6 145 ± 7a 148 ± 6a 153 ± 8a 131 ± 5a
 Treatment 99 ± 4 125 ± 9a 139 ± 12 126 ± 9 122 ± 2 132 ± 7a 129 ± 5a
CI, l/min/m2
 Sham 6.3 ± 0.2 7.3 ± 0.2 7.1 ± 0.4 7.2 ± 0.4 6.4 ± 0.4 7.5 ± 0.6 6.0 ± 0.5
 Control 6.4 ± 0.2 7.4 ± 0.5 6.6 ± 0.8 7.1 ± 0.6 6.3 ± 0.5 6.6 ± 0.7 6.7 ± 0.4
 Treatment 6.5 ± 0.3 6.6 ± 0.5 7.7 ± 0.9 7.0 ± 0.5 7.2 ± 0.6 7.3 ± 0.2 7.6 ± 0.7
LAP, mmHg
 Sham 9 ± 0 12 ± 2 13 ± 2 11 ± 1 11 ± 1 11 ± 1 11 ± 1
 Control 8 ± 1 10 ± 1 9 ± 1 11 ± 1 11 ± 1 10 ± 1 12 ± 2
 Treatment 9 ± 0 11 ± 1 11 ± 1 12 ± 1 12 ± 1 11 ± 1 10 ± 1
PCWP, mmHg
 Sham 11 ±0 16 ± 1 17 ± 1 16 ± 1 15 ± 1 16 ± 1 16 ± 1
 Control 11 ± 1 14 ± 1 14 ± 1 16 ± 1 16 ± 1 14 ± 1 14 ± 1
 Treatment 13 ± 0 16 ± 1 17 ± 1 17 ± 1 17 ± 1 17 ± 0 15 ± 0
MPAP, mmHg
 Sham 19 ± 0 28 ± 1 28 ± 1 27 ± 0 25 ± 1 29 ± 1 25 ± 1
 Control 19 ± 1 26 ± 1 26 ± 2 27 ± 1 29 ± 1 27 ± 1 28 ± 2
 Treatment 21 ± 0 29 ± 2 27 ± 2 27 ± 2 27 ± 1 27 ± 1 26 ± 1

CI, cardiac index; HR, heart rate; LAP, left atrial pressure; MAP, mean arterial pressure; MPAP, mean pulmonary arterial pressure; PCWP, pulmonary capillary wedge pressure. The data are expressed as mean ± SEM.

a

P < 0.05 vs. sham;

b

P < 0.05 treatment vs. control.