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. Author manuscript; available in PMC: 2013 Sep 19.
Published in final edited form as: JAMA. 2012 Jan 4;307(1):47–55. doi: 10.1001/jama.2011.1918

Table.

Body Composition and Energy Metabolism at Baseline and Changes During 8 Weeks of Overfeeding

Baseline
Change from Baselinea
Protein Diet Group, Mean (SD)b
P Valuec Protein Diet Group, Mean (95% CI)
P Valuec
Low: 5% Normal: 15% High: 25% Low: 5% Normal: 15% High: 25%
Age, y 22.9 (2.75) 22.9 (5.49) 26.8 (1.98) .08

Sex, No.
 Male 5 6 5

 Female 3 3 3

Race, No.
 White 4 0 3

 Black 3 8 5

 Asian 1 1 0

Weight, kg 69.1 (11.6) 77.6 (13.0) 76.0 (15.4) .40 3.16 (1.88 to 4.44) 6.05 (4.84 to 7.26) 6.51 (5.23 to 7.79) .002

Fat mass, kg 16.6 (5.07) 18.3 (7.40) 19.6 (6.38) .66 3.66 (2.82 to 4.49) 3.45 (2.67 to 4.24) 3.44 (2.60 to 4.27) .91

Lean body mass, kg 53.2 (10.3) 59.9 (12.5) 57.1 (13.5) .53 −0.70 (−1.50 to 0.10) 2.87 (2.11 to 3.62) 3.18 (2.37 to 3.98) <.001

Energy expenditure, kJ/d
 Total 9334 (1505) 9096 (2207) 8736 (1893) .82 176 (−740 to 1095) 2186 (1321 to 3051) 1898 (974 to 2813) .007

 Resting 6475 (1413) 6207 (1069) 6153 (1187) .85 −86.1 (−343 to 171) 669 (426 to 911) 949 (690 to 1204) <.001

Physical activity leveld 1.48 (0.31) 1.48 (0.29) 1.43 (0.26) .94 0.021 (−0.13 to 0.18) 0.16 (0.019 to 0.31) 0.079 (−0.078 to 0.23) .38

Non–resting energy expenditure, kJ/d 1924 (1473) 1979 (1761) 1706 (1558) .12 245 (−668 to 1158) 1296 (435 to 2157) 756 (−156 to 1669) .24

Protein, g/d 85.2 (9.2) 92.0 (18.0) 93.3 (19.7) .57 −38.6 (−51.9 to −25.2) 47.6 (34.9 to 60.2) 135 (121 to 148) <.001

Energy intake, kJ/d 9457 (1047) 10357 (2139) 10395 (2194) .53 3866 (209) 4088 (209) 3783 (222) .13
a

Data for change from baseline were adjusted for age, sex, and baseline values.

b

Unless otherwise indicated.

c

Calculated using analysis of variance.

d

Calculated as total energy expenditure divided by resting energy expenditure.