Table 3.
Anatomic likelihood estimation (ALE) summary for Rct, L-MTLE, and R-MTLE analyses.
| Cluster # | Label | Volume (mm3) | Weighted center (x, y, z) | ALE Mx (× 102) | Total foci | % Rep | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| Rct | 1 | I | Hippocampus | 2112 | 32 | − 16 | − 18 | 7.8 | 23 | 77% |
| 2 | B | Thalamus | 1632 | 0 | − 17 | 9 | 3.7 | 18 | 55% | |
| – Med Dorsal Nuc | 3.7 | |||||||||
| – Vent Post Med Nuc | 3.4 | |||||||||
| 3 | I | Limbic Lobe.BA 30 | 176 | 25 | − 38 | 1 | 3.2 | 3 | 14% | |
| LTLE | 1 | I | Hippocampus | 904 | − 31 | − 16 | − 18 | 4.8 | 7 | 64% |
| 2 | I | Thalamus. Med Dorsal Nuc | 160 | 3 | − 16 | 5 | 2.5 | 3 | 27% | |
| RTLE | 1 | I | Hippocampus | 1184 | 34 | − 17 | − 17 | 3.5 | 12 | 82% |
| 2 | C | Thalamus. Vent Post Med Nuc | 200 | − 14 | − 17 | 7 | 2.5 | 2 | 18% | |
Rct = Rectified (R-MTLE foci + L-MTLE foci rectified to R hemisphere); L = left medial temporal lobe epilepsy; R = right medial temporal lobe epilepsy; ALEmx = maximum ALE score for listed cluster; B = bilateral; I = ipsilateral to epileptogenic hippocampus; C = contralateral to epileptogenic hippocampus; % Rep = number of studies contributing VBM foci to ALE cluster/number of total studies.
All (x, y, z) foci are reported in Montreal Neuroimaging Institute (MNI) space.
All tissue labels are derived from the Talairach Daemon.