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. Author manuscript; available in PMC: 2013 Sep 19.
Published in final edited form as: Arch Ophthalmol. 2009 May;127(5):613–621. doi: 10.1001/archophthalmol.2009.88

Figure 4.

Figure 4

Phosphorylated angiogenesis-related receptors and signal proteins in human vitreous before and after treatment with bevacizumab. A, Patient 2, classified as a responder, exhibited a 32% decrease in vascular endothelial growth factor receptor (VEGFR) Y1175 1 month after bevacizumab treatment in addition to decreases in c-KIT Y703, platelet-derived growth factor receptor β (PDGFRβ Y716, PDGFRβ Y751, and VEGFR Y996. B, In contrast, patient 7, classified as a nonresponder, exhibited a 56% decrease in VEGFR Y1175, but showed concomitant increases in c-KIT Y703, PDGFRβ Y716, and VEGFR Y996 after bevacizumab treatment. Levels of PDGFRβ Y751 were not above background for this patient.