Table 4.
Brain region | Healthy control |
|||||||
---|---|---|---|---|---|---|---|---|
Cluster |
Side | BA | MNI coordinate |
Z value | ||||
Size | p Value | x | y | z | ||||
HMR minus NMR | ||||||||
Insula | 11,477 | < 0.001 | L | − 30 | 18 | − 2 | 6.44 | |
R | 32 | 22 | 0 | 6.89 | ||||
Caudate | L | − 10 | 6 | 0 | 5.64 | |||
R | 12 | 8 | 4 | 5.18 | ||||
Putamen | L | − 22 | 10 | 12 | 4.25 | |||
R | 20 | 10 | 8 | 3.97 | ||||
Nucleus accumbens | L | − 12 | 2 | − 2 | 6.08 | |||
R | 14 | 8 | − 2 | 5.71 | ||||
Thalamus | L | − 8 | − 20 | 12 | 4.07 | |||
R | 6 | − 16 | 14 | 5.29 | ||||
Cerebellum | L | − 8 | − 76 | − 28 | 4.47 | |||
R | 6 | − 78 | − 22 | 3.92 | ||||
Postcentral gyrus | 3015 | < 0.001 | R | 40 | 52 | − 36 | 52 | 3.24 |
Inferior parietal lobule | R | 40 | 40 | − 52 | 38 | 6.28 | ||
Superior parietal lobule | R | 7 | 38 | − 64 | 54 | 5.32 | ||
Precuneus | L | 7 | − 6 | − 68 | 44 | 3.56 | ||
R | 7 | 8 | − 66 | 44 | 5.65 | |||
Middle frontal gyrus | 2152 | < 0.001 | R | 10 | 38 | 56 | 12 | 3.24 |
R | 46 | 50 | 32 | 30 | 4.24 | |||
R | 9 | 46 | 16 | 40 | 3.73 | |||
R | 6 | 40 | 6 | 56 | 4.39 | |||
Inferior frontal gyrus | R | 9 | 46 | 8 | 26 | 4.54 | ||
Medial frontal gyrus | 1641 | 0.001 | R | 9 | 6 | 34 | 36 | 5.43 |
Cingulate gyrus | L | 32 | − 8 | 16 | 48 | 5.11 | ||
R | 32 | 6 | 22 | 44 | 4.86 | |||
LMR minus NMR | ||||||||
Inferior frontal gyrus | 8493 | < 0.001 | L | 47 | − 30 | 20 | − 2 | 4.61 |
R | 47 | 32 | 20 | − 2 | 5.56 | |||
Insula | L | − 30 | 18 | − 4 | 5.15 | |||
R | 30 | 22 | 2 | 5.45 | ||||
Caudate | L | − 10 | 6 | 0 | 3.94 | |||
R | 14 | 10 | 6 | 4.54 | ||||
Putamen | L | − 20 | 4 | 16 | 3.98 | |||
R | 16 | 12 | 0 | 4.67 | ||||
Nucleus accumbens | L | − 10 | 6 | − 2 | 4.21 | |||
R | 12 | 4 | − 4 | 3.90 | ||||
Thalamus | L | − 12 | − 12 | 8 | 4.24 | |||
R | 12 | − 10 | 10 | 4.73 | ||||
Cerebellum | 5259 | < 0.001 | L | − 8 | − 74 | − 26 | 4.67 | |
R | 4 | − 76 | − 26 | 4.35 | ||||
Medial frontal gyrus | 1257 | 0.004 | L | 9 | − 8 | 28 | 34 | 3.18 |
R | 9 | 6 | 34 | 36 | 4.74 | |||
Cingulate gyrus | L | 32 | − 10 | 16 | 48 | 4.30 | ||
R | 32 | 6 | 22 | 44 | 4.26 | |||
Middle frontal gyrus | 1014 | 0.013 | R | 46 | 46 | 36 | 22 | 3.60 |
R | 9 | 50 | 28 | 36 | 3.81 | |||
R | 6 | 40 | 8 | 54 | 3.43 |
NMR, no monetary reward; L, left; R, right; BA, Brodmann's area; MNI, Montréal Neurological Institute. The extent threshold was set at p = 0.05 with a correction for multiple comparisons at the cluster level for the entire brain. The height threshold was set at p = 0.005 (uncorrected) at the voxel level.