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Dissociation constants (KD) for the binding of various ligands to PXR LBD.
| Compounds | Dissociation constants (KD) (μM) |
|---|---|
| Compound 1 | 0.10 |
| Compound 2 | 0.05 |
| Compound 3 | ND |
| Compound 5 | 0.03 |
| Compound 6 | 0.02 |
| Compound 7 | 0.04 |
| Compound 8 | 0.07 |
| Rifampicin | 0.08 |
