. Author manuscript; available in PMC: 2013 Sep 19.

Published in final edited form as: J Infect Dis. 2009 Jun 15;199(12):1872–1882. doi: 10.1086/598858

Table 4.

Distinguishing characteristics of subjects with complete and incomplete immunologic responses (IRs)

Parameter	Complete IR	Incomplete IR	P
PD-1 expression (%CD3⁺PD-1⁺)^a	8.59 ± 0.55^b	10.18 ± 1.15	.264
T cell activation (%CD4⁺ HLA-DR⁺)^c	8.61 ± 0.67	12.94 ± 2.45	.093
CCR5 expression (%CD4⁺CCR5⁺)^b	9.41 ± 0.77	12.10 ± 1.77	.191
IL-7 plasma level^a	17.46 ± 8.88	9.91 ± 2.84	.706
Age,^a years	33.46 ± 1.11	31.95 ± 1.67	.503
Pre-HAART CD4⁺ T cell count ^a,^d,^e	477.75 ± 23.55	218.47 ± 26.12	<.001
IL-7-induced pSTAT5^a	86.7± 0.70	77.13 ± 4.78	.005

NOTE. Data are the mean ± standard error. Subjects with complete and incomplete immunologic responses (IRs) were subjects who attained viral load suppression and who, at 5≥years after initiation of highly active antiretroviral therapy (HAART), had attained CD4⁺ cell counts of ≥500 and <500 cells/mm³, respectively. The length of follow-up did not differ between subjects with complete and incomplete IRs (see main text). IL, interleukin; PD-1, programmed death-1; pSTAT5, phosphorylated signal transducer and activator of transcription 5.

Forty-six subjects with complete IR; 20 subjects with incomplete IR.

Forty subjects with complete IR; 17 subjects with incomplete IR.

Thirty-four subjects with complete IR; 14 subjects with incomplete IR.

Expressed as the number of cells per cubic millimeter.

Mean of all CD4⁺ T cell count measurements during the 1 year before initiation of HAART.