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. Author manuscript; available in PMC: 2014 Sep 3.
Published in final edited form as: Structure. 2013 Jul 25;21(9):1683–1689. doi: 10.1016/j.str.2013.07.001

Figure 2.

Figure 2

Structure of the Lgr4/R-spondin complex. A. Two orthogonal views of the ligand/receptor complex. Lgr4 is colored in blue and R-spondin, in magenta. The inserts are superimpositions of ligand-bound (blue) and unliganded (green) Lgr4. Secondary structure elements in R-spondin are labeled. B. The Lgr4/R-spondin complex with either Lgr4 (Left Panel) or R-spondin complex (Right Panel) are drawn as solvent accessible surfaces and color-coded by electrostatic surface potential. This panel illustrates the complementary-charged surfaces that constitute the Lgr4/R-spondin interface.