Table 3.

Results of analyses of variance on ROI averaged FA values with and without the covariate sex; the anatomical location of the five different ROIs is depicted in Fig. 2; the degrees of freedom (d.f.) of each F-statistic is given in brackets. The listed values were obtained for differences between the HD and the control group.

	In the presence of the covariate sex				No covariates
	Group		Group-by-center		Group		Group-by-center
	F(1,92)	p	F(3,92)	p	F(1,93)	p	F(3,93)	p
Basal ganglia	28.22	< 0.001	1.54	0.209	27.56	< 0.001	2.42	0.071
External capsule	11.26	0.001	0.45	0.717	11.40	0.001	0.49	0.693
Thalamic region	19.14	< 0.001	0.84	0.475	19.38	< 0.001	1.27	0.288
Internal capsule	18.56	< 0.001	0.17	0.915	18.72	< 0.001	0.16	0.922
Corpus callosum	11.68	0.001	0.31	0.816	11.75	0.001	0.29	0.835