Figure 3. Downregulation of CD244 in a RSV-specific CD8 T cell clone.
A. A CD8 T cell clone specific for RSV-YY9 was incubated overnight in the presence or absence of cognate peptide. The expression of CD244, TIM-3, PD-1, CD8, and CD3 were determined by ICS. B. The experiment shown in A was repeated four times and the MFI of the markers shown was compared in the presence or absence of cognate peptide. * indicates Wilcoxon p<0.02.