Table 3. Factors associated with drug reactions, by organ system.
| Univariate Analysis | Multivariate Analysis | ||||
| Odds Ratio | P-Value | Odds Ratio | P-Value | ||
| Any Dermatologic ADE | Any Dermatologic ADE | ||||
| Twice-Weekly Evaluations | 2.057 | 0.030 | Twice-Weekly Evaluations | 1.944 | 0.066 |
| Female Sex | 5.232 | 0.002 | Female Sex | 3.131 | 0.002 |
| Abnormal ECG | 1.630 | 0.168 | Abnormal ECG | 2.252 | 0.037 |
| Sun Sensitivity | 8.182 | 0.075 | |||
| Moderate Dermatologic ADE | Moderate Dermatologic ADE | ||||
| Twice-Weekly Evaluations | 1.874 | 0.143 | Female Sex | 2.922 | 0.036 |
| Female Sex | 2.171 | 0.089 | Residence Within City of Punata | 5.048 | 0.040 |
| Residence Within City of Punata | 4.719 | 0.041 | Abnormal ECG | 3.905 | 0.005 |
| Abnormal ECG | 2.556 | 0.032 | Sun Sensitivity | 4.418 | 0.096 |
| Sun Sensitivity | 4.062 | 0.078 | |||
| Any Gastrointestinal ADE | Any Gastrointestinal ADE | ||||
| Twice-Weekly Evaluations | 1.653 | 0.132 | Female Sex | 2.071 | 0.038 |
| Female Sex | 2.135 | 0.029 | Sun Sensitivity | 4.812 | 0.069 |
| Cardiac Symptoms | 1.898 | 0.129 | |||
| Gastrointestinal Symptoms | 1.898 | 0.194 | |||
| Sun Sensitivity | 5.200 | 0.054 | |||
| Family History of Allergies | 5.007 | 0.024 | |||
| Any Neurological ADE | Any Neurological ADE | ||||
| Twice-Weekly Evaluations | 2.687 | 0.017 | Twice-Weekly Evaluations | 2.832 | 0.015 |
| Female Sex | 1.232 | 0.603 | Sun Sensitivity | 6.961 | 0.018 |
| Sun Sensitivity | 6.000 | 0.024 | |||
| Self-Reported Allergies | 1.891 | 0.149 | |||
| Neuropathy Before Treatment | 4.913 | 0.121 | |||