Table 1. Mutations in housekeeping genes from 100 Indian Plasmodium vivax isolates.
| Housekeeping gene | Gene ID | Fragment size (bp) | Coding sites (bp) | Non-coding sites (bp) | Segregating sites | Synonymous substitution | Non-Synonymous substitution | Non-coding substitution | Total changes | Haplotype diversity (Hd) | Nucleotide diversity (π) |
| Ribosomal protein l35e | PVX_091865 | 518 | 170 | 348 | 12 | 2 | 5 | 5 | 13 | 0.665 | 0.00188 |
| Exonuclease Domain | PVX_003660 | 300 | 300 | 0 | 1 | 1 | 0 | 0 | 1 | 0.366 | 0.00119 |
| Adenylate Cyclase | PVX_092535 | 496 | 496 | 0 | 3 | 2 | 1 | 0 | 3 | 0.614 | 0.00146 |
| Acyl Carrier Protein | PVX_114420 | 1336 | 706 | 630 | 10 | 3 | 3 | 4 | 10 | 0.494 | 0.00083 |
| Serine threonine protein kinase | PVX_113435 | 1103 | 619 | 484 | 4 | 0 | 2 | 2 | 4 | 0.169 | 0.00016 |
| Ribosomal protein l34a | PVX_088065 | 1134 | 586 | 548 | 7 | 0 | 0 | 7 | 7 | 0.864 | 0.00132 |
| RNA Polymerase-II | PVX_122080 | 984 | 532 | 452 | 9 | 0 | 1 | 8 | 9 | 0.677 | 0.00106 |
| Enolase | PVX_095015 | 1160 | 557 | 603 | 20 | 2 | 5 | 13 | 20 | 0.837 | 0.00147 |
| DNA Gyrase | PVX_123795 | 1162 | 507 | 655 | 7 | 3 | 3 | 1 | 7 | 0.741 | 0.00092 |
| Calcium dependent protein kinase | PVX_119610 | 1105 | 802 | 302 | 2 | 0 | 0 | 2 | 2 | ND | ND |
| Total | 9298 | 5275 | 4022 | 75 | 13 | 20 | 42 | 76 |
ND: not determined.