Table 2. Neutrality test and mutation parameter of Plasmodium vivax housekeeping genes on the Indian subcontinent.
| Gene | Tajima's D | Fu & Li's D | dN±SE (10−3) | dS±SE (10−3) | dN = / = dS | Theta (θ) per site | Nucleotide substitutions rates in Pv | Divergence rates between Pv & Pk | ||
| dS | dN | Ks | Ka | |||||||
| ed | 1.027 | 0.491 | 0.00 | 2.0±2.0 | 1.005 | 0.00064* | 0.00 | 0.002±0.002 | 0.4334 | 0.1181 |
| ac | −0.421 | −0.804 | 7.0±5.0 | 0.00 | −1.151 | 0.00173 | 0.00 | 0.001±0.001 | 0.3399 | 0.0410 |
| acp-in | −0.434 | 1.006 | - | - | - | 0.00126 | 0.00 | 0.000 | 0.2907 | 0.0257 |
| acp-ex | −1.36 | −1.726 | 2.0±2.0 | 0.00 | −0.955 | 0.00166 | 0.00 | 0.001±0.001 | 0.4202 | 0.1423 |
| l35e | −1.543 | −2.92 | 0.00 | 1.0±1.0 | 2.074 | 0.00448 | 0.004±0.003 | 0.000 | 0.3798 | 0.0134 |
| l34a | 0.231 | −0.557 | 0.00 | 0.000 | - | 0.0012 | 0.00 | 0.0025±0.002 | 0.2332 | 0.0068 |
| stpk | −1.487 | −1.437 | 0.00 | 0.000 | 1.418 | 0.0007* | 0.002±0.002 | 0.000 | 0.2575 | 0.0320 |
| enolase | −1.624 | −3.617 | 4.0±3.0 | 0.000 | −1.035 | 0.00332 | 0.000 | 0.000 | 0.6643 | 0.5624 |
| RNA pol | −1.031 | −1.651 | 0.00 | 2.5±2.0 | 0.992 | 0.00179 | 0.007±0.005 | 0.000 | 0.5496 | 0.0867 |
| dg | −0.501 | −0.547 | 0.00 | 1.0±1.0 | 2.061 | 0.00117 | - | - | 0.6966 | 0.7130 |
| Mean | 0.002076±0.00059 | 0.004±0.001 | 0.0016±0.0003 | 0.3965 | 0.1142 | |||||
Boldface values are statistically significant (p<0.05), *excluded in averaging θ, Pv: Plasmodium vivax, Pk: P. knowlesi, dS: synonymous substitution rate, dN: non-synonymous substitution rate, Ks: synonymous divergence rate, Ka: non synonymous divergence rate.