Table 2. Temephos resistance candidate genes ranked according to the fold change in expression between CucR and CucU, with detoxification genes shown in bold.
Fold change | |||||
Systematic name | Description | CucR-NO | CucR-BB | CucR-CucU | CucP-CucR |
AAEL011230-RA | Chymotrypsin, putative | 87.14 | 28.37 | 30.21 | −122.93 |
AAEL011167-RA | Cathepsin l | 5.44 | 17.50 | 13.21 | −4.32 |
AAEL001418-RA | Conserved hypothetical protein | 26.24 | 4.70 | 13.00 | −28.75 |
AAEL003076-RA | Glucosyl/glucuronosyl transferase | 13.65 | 16.09 | 10.38 | −22.37 |
AAEL015657-RA | Conserved hypothetical protein | 14.54 | 13.51 | 8.14 | −10.77 |
AAEL013263-RA | High affinity copper transporter, putative | 4.41 | 9.73 | 6.73 | −11.13 |
AAEL014843-RA | Heat shock protein | 11.50 | 6.21 | 5.87 | −3.21 |
AAEL011175-RA | Alkaline phosphatase | 6.18 | 12.77 | 5.70 | −7.80 |
AAEL000813-RA | Dimethylaniline monooxygenase | 3.23 | 2.54 | 5.39 | −6.71 |
AAEL015010-RA | Acetyl-coa synthetase | 7.12 | 5.27 | 5.23 | −5.23 |
AAEL015070-RA | Alkaline phosphatase | 5.08 | 13.50 | 5.09 | −6.85 |
AAEL006820-RA | Lipid storage droplets surface binding protein 2 (lsd2) | 4.72 | 4.03 | 4.78 | −2.49 |
AAEL001194-RA | Fatty acid synthase | 5.47 | 3.23 | 4.14 | −4.55 |
AAEL011704-RA | Heat shock protein | 8.23 | 2.20 | 4.13 | −3.05 |
AAEL007799-RA | Regulator of chromosome condensation | 3.74 | 2.21 | 3.46 | −2.88 |
AAEL007799-RB | Regulator of chromosome condensation | 3.74 | 2.27 | 3.46 | −2.83 |
AAEL004455-RA | Conserved hypothetical protein | 3.62 | 2.16 | 3.12 | −2.72 |
AAEL008651-RA | Conserved hypothetical protein | 3.45 | 28.44 | 3.12 | −3.97 |
AAEL008844-RA | Calcium-binding protein, putative | 2.41 | 4.62 | 3.08 | −5.07 |
AAEL008723-RA | Conserved hypothetical protein | 4.36 | 2.01 | 2.92 | −2.62 |
AAEL005045-RA | ATP-dependent bile acid permease | 3.38 | 2.61 | 2.89 | −7.49 |
AAEL000520-RA | Conserved hypothetical protein | 5.77 | 2.95 | 2.58 | −3.46 |
AAEL012185-RA | Ribosome biogenesis regulatory protein | 2.93 | 2.77 | 2.58 | −2.46 |
AAEL010118-RA | Kelch repeat protein | 3.20 | 2.03 | 2.57 | −2.29 |
AAEL012100-RA | Conserved hypothetical protein | 3.18 | 3.11 | 2.43 | −2.47 |
AAEL013406-RA | Venom allergen | 7.90 | 4.23 | 2.42 | −9.90 |
AAEL005991-RA | Tricarboxylate transport protein | 2.21 | 4.37 | 2.38 | −3.10 |
AAEL003654-RA | Conserved hypothetical protein | 3.41 | 2.19 | 2.38 | −2.16 |
AAEL009124-RA | Cytochrome P450 CYP6N12 | 3.98 | 4.40 | 2.34 | −4.77 |
AAEL009127-RA | Cytochrome P450 CYP6M11 | 3.82 | 3.13 | 2.32 | −2.25 |
AAEL007271-RA | Basic helix-loop-helix zip transcription factor | 4.97 | 4.11 | 2.30 | −3.41 |
AAEL012866-RA | Conserved hypothetical protein | 3.88 | 4.38 | 2.29 | −3.31 |
AAEL008281-RA | Conserved hypohetical protein | 2.73 | 3.37 | 2.28 | −5.23 |
AAEL003949-RA | Conserved hypothetical protein | 2.50 | 2.55 | 2.26 | −2.06 |
AAEL008124-RA | Possible RNA methyltransferase, putative | 2.92 | 2.55 | 2.25 | −2.01 |
AAEL000300-RA | WD-repeat protein | 2.71 | 2.09 | 2.24 | −2.08 |
AAEL013946-RA | Conserved hypothetical protein | 3.88 | 5.35 | 2.17 | −2.61 |
AAEL004063-RA | WD-repeat protein | 2.90 | 2.50 | 2.08 | −2.07 |
AAEL002913-RA | Peroxisomal membrane protein 70 abcd3 | 4.41 | 2.47 | 1.74 | −2.39 |
AAEL014684-RA | Cytochrome P450 CYP6F3 | 3.35 | 7.22 | 1.71 | −4.68 |
AAEL001813-RA | Sodium/solute symporter | 3.08 | 2.70 | 1.66 | −2.11 |
P-values and corrected P-values are shown in Table S3c.