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. 2013 Sep 19;7(9):e2435. doi: 10.1371/journal.pntd.0002435

Table 2. Demographic data and symptoms of patients.

Variable No diagnosis (n = 157) Acute hepatitis A (n = 26)a Acute hepatitis B (anti-HBc IgM +ve) (n = 21)b Presumed chronic hepatitis B (anti-HBc IgM −ve) (n = 37)c Presumed chronic hepatitis C (n = 20)d
Male/female, % 64/36 77/23 71/29 76/24 74/26
Missing data, n 6 4 1
Age in years, median (Q25–Q75) 18 (4–30)e 5 (3–7)e 30 (18–35)e 30 (26–35)e 32 (25–49)e
Missing data, n 5 1 5 1
Region, n (%)
Brong-Ahafo & Ashanti 49 (31) 10 (38) 5 (24) 9 (24) 3 (15)
Northern 50 (32)f 9 (35) 11 (52)f 26 (70)f 11 (55)
Upper West & East 58 (37)g 7 (27) 5 (24)g 2 (5)g 6 (30)
Symptoms, n (%)
Fever 115 (73) 21 (81) 17 (81) 30 (81) 10 (50)
Jaundice 61 (39)h 20 (77)h 17 (81)h 19 (51) 7 (35)
Hemorrhage 23 (15) 3 (12) 2 (10) 3 (8) 2 (10)
Missing data, n 1

Statistical analysis of the data: Each sub-group with diagnosis was tested vs. the sub-group without diagnosis for all quantitative variables and categories of a qualitative variable. Statistically significant differences are indicated by footnotes; all other differences were not significant.

Abbreviations: Q25, lower quartile, 25% of the data lie below this value; Q75, upper quartile, 75% of the data lie below this value.

a

18 patients were positive for anti-HAV IgM and HAV RNA; 7 patients were positive for anti-HAV IgM; 1 patient was positive for HAV RNA. Co-infections: 1 patient was positive for HBV DNA and HBsAg.

b

19 patients were positive for anti-HBc IgM, HBV DNA, and HBsAg; 2 patients were positive for anti-HBc IgM and positive for HBV DNA in two different PCR assays, but negative for HBsAg. Co-infections: 1 patient was HCV RNA positive.

c

All patients were positive for HBV DNA and HBsAg, but negative for anti-HBc IgM. Co-infections: 1 patient was anti-HAV IgM positive; 1 patient was HCV RNA positive.

d

All patients were HCV RNA positive. Co-infections: 1 patient was positive for anti-HBc IgM, HBV DNA, and HBsAg; 1 patient was positive for HBV DNA and HBsAg.

e

p = 0.001, no diagnosis vs. acute hepatitis A; p = 0.0001, no diagnosis vs. chronic hepatitis B; p = 0.00004, no diagnosis vs. acute & chronic hepatitis B combined; p = 0.005, no diagnosis vs. hepatitis C.

f

p<0.0001, no diagnosis vs. chronic hepatitis B; p<0.0001, no diagnosis vs. acute & chronic hepatitis B combined.

g

p<0.0001, no diagnosis vs. chronic hepatitis B; p = 0.0004, no diagnosis vs. acute & chronic hepatitis B combined.

h

p = 0.0005, no diagnosis vs. acute hepatitis A; p = 0.0003, no diagnosis vs. acute hepatitis B.