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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: Curr Allergy Asthma Rep. 2013 Oct;13(5):434–442. doi: 10.1007/s11882-013-0354-z

Table 3.

Effects of treatment of OSA in Asthma

Study Subjects Methodology Findings
Chan
1987(32)		 9 patients with
nocturnal
asthma and
OSA		 CPAP for sleep apnea Nocturnal asthma control and
PEFR improved
Lyn 1995 (33) 48 patients: 16
with OSA, 16
with snoring
and 16 controls		 Pre and post CPAP
treatment
Methacholine
(MCT)challenge( only
positive MCT patients
received CPAP)		 Reduced bronchial reactivity
after CPAP
Lafond 2007
(34)		 20 patients
with asthma
and OSA		 Bronchial reactivity,
spirometry and
asthma QOL
questionnaire		 Asthma quality of life improved,
but no change in FEV1 or
bronchial reactivity.
Cifti 2005
(35)		 43 patients
with asthma		 PSG and treated with
CPAP		 Asthma night-time symptom
scores were improved
significantly. Lung function did
not improve