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. 2013 May 14;35(5):1801–1814. doi: 10.1002/hbm.22295

Table 3.

Comparisons of PDCP network and subject scores with FDG PET images normalized by four versions of SPM software

SPM99 SPM2 SPM5 SPM8
VAF (%) 19.28 20.92 20.65 20.81
GIS weightsa 1.000/1.000 0.976/0.949 0.968/0.940 0.970/0.943
PCA derivation sample
15 PD 0.864 ± 0.312 0.640 ± 0.325 0.608 ± 0.326 0.617 ± 0.325
CVLT −0.727b −0.661c −0.645c −0.650c
TPR validation sample
15 PD2 1.087 ± 0.236 0.883 ± 0.225 0.851 ± 0.222 0.856 ± 0.222
CVLT −0.503d −0.610d −0.612d −0.610d
CVLT 30 PD −0.650a −0.642a −0.632a −0.635a
Subject score correlationa
15 PD 1.000 0.965 0.957 0.959
15 NC 1.000 0.948 0.947 0.952
15 PD2 1.000 0.975 0.970 0.973

VAF, variance accounted for in principal component analysis; GIS, Group Invariant Subprofile from the derivation sample of patients with PD.

The correlations of the GIS weights were performed over a standard 30 VOI template with a threshold of 80% or over all voxels of the brain with non‐zero values.

All average values are given as mean ± SE.

a

P < 0.0001; Pearson correlation coefficient from regression analysis.

b

P < 0.005.

c

P < 0.01.

d

P < 0.05.