Table 3.
Comparisons of PDCP network and subject scores with FDG PET images normalized by four versions of SPM software
SPM99 | SPM2 | SPM5 | SPM8 | |
---|---|---|---|---|
VAF (%) | 19.28 | 20.92 | 20.65 | 20.81 |
GIS weightsa | 1.000/1.000 | 0.976/0.949 | 0.968/0.940 | 0.970/0.943 |
PCA derivation sample | ||||
15 PD | 0.864 ± 0.312 | 0.640 ± 0.325 | 0.608 ± 0.326 | 0.617 ± 0.325 |
CVLT | −0.727b | −0.661c | −0.645c | −0.650c |
TPR validation sample | ||||
15 PD2 | 1.087 ± 0.236 | 0.883 ± 0.225 | 0.851 ± 0.222 | 0.856 ± 0.222 |
CVLT | −0.503d | −0.610d | −0.612d | −0.610d |
CVLT 30 PD | −0.650a | −0.642a | −0.632a | −0.635a |
Subject score correlationa | ||||
15 PD | 1.000 | 0.965 | 0.957 | 0.959 |
15 NC | 1.000 | 0.948 | 0.947 | 0.952 |
15 PD2 | 1.000 | 0.975 | 0.970 | 0.973 |
VAF, variance accounted for in principal component analysis; GIS, Group Invariant Subprofile from the derivation sample of patients with PD.
The correlations of the GIS weights were performed over a standard 30 VOI template with a threshold of 80% or over all voxels of the brain with non‐zero values.
All average values are given as mean ± SE.
P < 0.0001; Pearson correlation coefficient from regression analysis.
P < 0.005.
P < 0.01.
P < 0.05.