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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: Pain. 2013 Jun 15;154(10):2024–2033. doi: 10.1016/j.pain.2013.06.019

Figure 4. Intrathecal application of FK-506 elicited mechanical and thermal hypersensitivity in control, uninjured animals.

Figure 4

Ninety minutes after an intrathecal injection of the calcineurin inhibitor FK-506 there was a significant decrease in withdrawal thresholds and latencies in control, uninjured, animals. In these same animals there was also a significant decrease in calcineurin activity in their PSD #p<0.005, *p<0.001.