Table 2.
Voxel-based morphometry results showing regions of significant grey matter intensity decrease that covary with episodic memory recall performance for C9 patients contrasted with Controls.
Regions | Hemisphere | MNI coordinates |
Number of voxels |
||
---|---|---|---|---|---|
x | y | z | |||
Temporal fusiform cortex, parahippocampal cortex, inferior temporal gyrus | Left | − 30 | − 12 | − 42 | 805 |
Parietal operculum cortex, superior parietal lobule | Left | − 46 | − 40 | 32 | 640 |
Temporal fusiform cortex, parahippocampal cortex, hippocampus | Right | 34 | − 2 | − 50 | 637 |
Orbitofrontal cortex, inferior frontal gyrus | Left | − 48 | 30 | − 12 | 550 |
Supramarginal gyrus, superior parietal lobule | Right | 42 | − 30 | 34 | 495 |
Inferior temporal gyrus | Right | 58 | − 40 | − 26 | 384 |
Middle temporal gyrus | Left | − 50 | − 18 | − 16 | 301 |
Supracalcarine cortex, precuneus | Right | 18 | − 70 | 16 | 286 |
Precentral gyrus | Left | − 22 | − 28 | 52 | 250 |
Temporal pole | Left | − 28 | 18 | − 30 | 236 |
Frontal pole | Right | 18 | 48 | − 10 | 204 |
Middle frontal gyrus | Left | − 38 | 10 | 54 | 179 |
Superior temporal gyrus | Right | 46 | − 32 | 8 | 177 |
Insular cortex | Left | − 26 | 12 | 14 | 175 |
Frontal operculum cortex | Right | 36 | 22 | 14 | 169 |
Temporal pole | Right | 52 | 24 | − 18 | 147 |
Frontal pole | Left | − 16 | 52 | − 10 | 143 |
Posterior cingulate cortex | Bilateral | − 2 | − 18 | 44 | 124 |
Postcentral gyrus | Right | 18 | − 38 | 50 | 122 |
Orbitofrontal cortex | Left | − 10 | 32 | − 22 | 122 |
Occipital pole | Right | 20 | − 104 | − 8 | 104 |
All results uncorrected at p < .01; for brevity only clusters with at least 100 contiguous voxels are reported here. Education is included as a covariate in all contrasts. All clusters reported t > 2.82.