Table 4. Response subgroups 1, 2, 3 and 4: criteria for subgrouping of individual lesions based on change in size and change in enhancement.

	Response criteria for individual lesions
Response subgroup 1	⩾30% reduction in size
	⩾50% reduction in nE
Response subgroup 2	<30% reduction in size, and <20% increase in size
	⩾50% reduction in nE
Response subgroup 3	<30% reduction in size, and <20% increase in size
	<50% reduction in nE
Response subgroup 4	⩾20% increase in size
	<50% reduction in nE

Abbreviation: nE=normalised mean enhancement.