Figure 4.
The Pyk2[pY881] staining in different tissues by immunohistochemical staining. (A) As can be observed, Pyk2[pY881] shows cytoplasmic staining in primary lung carcinoma lesions ( × 400). (B, C) Protein expression of Pyk2[pY881] is much higher in primary lung cancer lesions than in the adjacent noncancerous tissues (B × 40; C × 400). (D, E) The Pyk2[pY881] shows strong cytoplasmic staining in the corresponding metastatic lymph nodes of squamous carcinoma (D × 100; E × 400) and (F, G) metastatic brain lesions of adenocarcinoma (F × 100; G × 400).