Table 3. Factors associated with non-compliance in the pre-surgery group (N=692).
|
|
Univariate analysis |
Multivariate analysis |
||
---|---|---|---|---|---|
Compliant decisions N=652, N (%) | Non-compliant decisions N=40, N (%) | P-value | OR (95% CI) | P-value | |
Age at diagnosis, years |
|
|
<0.0001 |
|
|
⩽35 | 28 (90.3) | 3 (9.7) | 2.8 (0.8–9.9) | 0.1 | |
35–80 | 573 (96.3) | 22 (3.7) | 1 | ||
⩾80 |
51 (77.3) |
15 (22.7) |
|
7.7 (3.7–15.7) |
<0.0001 |
Postmenopausal status |
|
|
0.5 |
|
|
No | 234 (95.1) | 12 (4.9) | |||
Yes |
406 (93.6) |
28 (6.4) |
|
|
|
Tumour size, mm |
|
|
0.3 |
|
|
⩽20 | 320 (95.5) | 15 (4.5) | |||
20–40 | 202 (92.7) | 16 (7.3) | |||
⩾40 |
130 (93.5) |
9 (6.5) |
|
|
|
Multifocal tumour |
|
|
0.3 |
|
|
No | 534 (93.7) | 36 (6.3) | |||
Yes |
118 (96.7) |
4 (3.3) |
|
|
|
Microinvasive tumour |
|
|
1.0 |
|
|
No | 637 (94.1) | 40 (5.9) | |||
Yes |
15 (100.0) |
0 (0.0) |
|
|
|
Prior neoadjuvant treatment |
|
|
0.08 |
|
|
No | 597 (94.8) | 33 (5.2) | |||
Yes |
55 (88.7) |
7 (11.3) |
|
|
|
Contraindications to surgery |
|
|
0.4 |
|
|
No | 620 (94.4) | 37 (5.6) | |||
Yes |
32 (91.4) |
3 (8.6) |
|
|
|
Frequent patient profile |
|
|
0.03 |
|
|
No | 117 (90.0) | 13 (10.0) | |||
Yes | 535 (95.2) | 27 (4.8) |
Abbreviations: CI=confidence interval; OR=odds ratio.
Twelve missing data for postmenopausal status in compliant decisions. Fisher's exact test used for categorical variables in the univariate analysis. Variables with P<0.20 in the univariate analysis (age at diagnosis, prior neoadjuvant treatment, and frequent patient profile) entered the multivariate analysis.