Table 2. Toxicity of cetuximab+chemoradio- or chemotherapy.
| Locally advanced | Metastatic | |||
|---|---|---|---|---|
|
Toxicity |
All grades |
Grades 3 and 4 |
All grades |
Grades 3 and 4 |
| |
n
(%) |
n
(%) |
n
(%) |
n
(%) |
| Skin rash |
9 (100) |
6 (67) |
11 (92) |
4 (33) |
| In-field dermatitis |
7 (78) |
6 (67) |
— |
— |
| Mucositis |
8 (89) |
6 (67) |
5 (38) |
1 (8) |
| Vomiting |
9 (100) |
0 |
8 (67) |
1 (8) |
| Diarrhoea |
0 |
0 |
4 (25) |
1 (8) |
| Neutropenia |
1 (11) |
0 |
1 (8) |
0 |
| Neutropenic fever |
0 |
0 |
2 (17) |
2 (17) |
| Polineuropathy |
2 (22) |
0 |
2 (17) |
0 |
| Paronychia |
1 (11) |
0 |
2 (17) |
2 (17) |
| Haematologic |
0 |
0 |
2 (17) |
0 |
| Renal |
0 |
0 |
2 (17) |
0 |
| Ototoxicity |
0 |
0 |
2 (17) |
0 |
| Fatigue | 4 (44) | 0 | 1 (8) | 0 |