Table 4.
Product conversion obtained for four aldehyde substrates in the Biginelli reaction with ethyl acetoacetate and urea.
 | ||
| R | Product | Conv. (%) |
| H | 4a | 88 (78)a |
| OMe | 4b | 85 |
| Me | 4c | 87 |
| F | 4d | 91 |
aIsolated yield.
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