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. Author manuscript; available in PMC: 2014 Sep 6.
Published in final edited form as: J Org Chem. 2013 Aug 13;78(17):8859–8864. doi: 10.1021/jo401249y

Table 2.

Scope of the coupling of aryl halides and triflates with 10 equiv nitromethane.graphic file with name nihms-513605-t0002.jpg

entry substrate yield (%)a entry substrate yield (%)a
1 graphic file with name nihms-513605-t0003.jpg 94 8 graphic file with name nihms-513605-t0004.jpg 77
2 graphic file with name nihms-513605-t0005.jpg 77 9 graphic file with name nihms-513605-t0006.jpg 50b
3 graphic file with name nihms-513605-t0007.jpg 82 10 graphic file with name nihms-513605-t0008.jpg 77b
4 graphic file with name nihms-513605-t0009.jpg 70 11 graphic file with name nihms-513605-t0010.jpg 86
5 graphic file with name nihms-513605-t0011.jpg 82 12 graphic file with name nihms-513605-t0012.jpg 86
6 graphic file with name nihms-513605-t0013.jpg 90 13 graphic file with name nihms-513605-t0014.jpg 24
7 graphic file with name nihms-513605-t0015.jpg 80
a

Yield after column chromatography.

b

5 mol% Pd2dba3, 12 mol% XPhos, 80 °C.