TABLE 3.
BLOOD VESSEL VOLUME RATIOS FOR THE NEVER-SMOKERS AND SMOKERS
| Variable | Distribution of Blood Vessel Volume Ratios |
P Value* | P Value† | |||||
|---|---|---|---|---|---|---|---|---|
| Never-Smoking Control Subjects | Smoking Control Subjects | GOLD1 | GOLD2 | GOLD3 | GOLD4 | |||
| Whole right lung |
|
|
|
|
|
|
|
|
| BV5right/TBVright |
0.58 (0.55–0.61) |
0.57 (0.54–0.60) |
0.56 (0.52–0.58) |
0.55 (0.52–0.59) |
0.53 (0.49–0.56) |
0.52 (0.47–0.54) |
0.25 |
<0.0001 |
| BV5right/TissueVright |
0.021 (0.019–0.024) |
0.020 (0.018–0.023) |
0.019 (0.016–0.021) |
0.019 (0.018–0.022) |
0.019 (0.017–0.022) |
0.019 (0.017–0.023) |
0.25 |
0.34 |
| Right upper lobe |
|
|
|
|
|
|
|
|
| BV5RUL/TBVRUL |
0.62 (0.59–0.66) |
0.61 (0.58–0.65) |
0.60 (0.56–0.63) |
0.59 (0.55–0.63) |
0.56 (0.53–0.60) |
0.55 (0.51–0.60) |
0.15 |
<0.0001 |
| BV5RUL/TissueVRUL |
0.022 (0.020–0.026) |
0.020 (0.017–0.024) |
0.018 (0.016–0.022) |
0.019 (0.017–0.022) |
0.020 (0.016–0.022) |
0.019 (0.017–0.022) |
0.001 |
0.37 |
| Right lower lobe |
|
|
|
|
|
|
|
|
| BV5RLL/TBVRLL |
0.56 (0.53–0.59) |
0.56 (0.52–0.58) |
0.53 (0.50–0.58) |
0.53 (0.50–0.57) |
0.51 (0.47–0.54) |
0.49 (0.45–0.52) |
0.46 |
<0.0001 |
| BV5RLL/TissueVRLL | 0.022 (0.019–0.025) | 0.022 (0.019–0.025) | 0.020 (0.017–0.022) | 0.021 (0.019–0.025) | 0.020 (0.019–0.024) | 0.021 (0.019–0.023) | 0.68 | 0.51 |
Definition of abbreviations: BV5right/TBVright = blood vessel volume less than 5 mm2 in the whole right lung divided by the total intraparenchymal blood vessel volume in the whole right lung; BV5RUL/TBVRUL = blood vessel volume less than 5 mm2 in the right upper lobe divided by the total intraparenchymal blood vessel volume in the right upper lobe; BV5RLL/TBVRLL = blood vessel volume less than 5 mm2 in the right lower lobe divided by the total intraparenchymal blood vessel volume in the right lower lobe; BV5right/TissueVright = blood vessel volume less than 5 mm2 in the whole right lung divided by the total nonvascular tissue volume in the whole right lung; BV5RUL/TissueVRUL = blood vessel volume less than 5 mm2 in the right upper lobe divided by the nonvascular tissue volume of the right upper lobe; BV5RLL/TissueVRLL = blood vessel volume less than 5 mm2 in the right lower lobe divided by the nonvascular tissue volume of the right lower lobe; GOLD = Global Initiative for Chronic Obstructive Lung Disease; RLL = right lower lobe; RUL = right upper lobe.
Volumes are presented as medians and interquartile ranges.
P value for difference in medians between never-smokers and smoking control subjects (smokers with normal lung function).
P value for trend test across GOLD 1–4.