TABLE 4.

Characteristics of studies included in meta-analysis of randomized controlled trials in adults

Reference	Study population	Sample size	Mean ± SD baseline age and/or age range	Mean ± SD baseline BMI and/or BMI range	Duration	Design	Study question	Intervention	Control
Tordoff, 1990 (69)	USA	9 women and 21 men	Women: 28.2 ± 2.7 y; men: 22.9 ± 0.8 y	Women: 25.4 ± 1.4; men: 25.1 ± 0.5	3 wk	Crossover	Adding HFCS1 soda to the normal diet and changes in body weight compared with diet soda with aspartame	1135 mL soda including 133 g HFCS/d (530 kcal)	1135 mL diet soda including 590 mg aspartame/d, no calories
Reid, 2007 (66)	UK	133 women	31.8 ± 9.1 y; 20–55 y	22.5 ± 2.8; range: <25	4 wk	Parallel	Adding sucrose beverages to the normal diet and changes in body weight compared with artificially sweetened beverages	1 L sucrose-sweetened drinks (1800 kJ/d)	1 L artificially sweetened drinks (67 kJ/d)
Reid, 2010 (67)	UK	53 overweight women	34.5 ± 11.0 y in the intervention group and 32.9 ± 8.8 y in the control group; 20–55 y	27.2 ± 2.06 in the intervention group and 27.8 ± 1.8 in the control group; 25–30	4 wk	Parallel	Adding sucrose beverages to the normal diet and changes in body weight compared with artificially sweetened beverages	1 L sucrose-sweetened drinks (1800 kJ/d)	1 L artificially sweetened drinks (67 kJ/d)
Aeberli, 2011 (70)	Switzerland	29 healthy-weight men	26.3 ± 6.6 y	22.4 ± 1.9	3 wk	Crossover	Adding sucrose beverages to the normal diet and changes in body weight compared with dietary advice	600 mL drinks including 80 g sucrose/d	Dietary advice aimed at reducing free fructose intake
Maersk, 2012 (68)	Denmark	30 women and 17 men who were overweight	Mean: ∼39 y; 20–50 y	Mean: ∼32; 26–40	6 mo	Parallel	Adding sucrose beverages to the normal diet and changes in body weight compared with 3 other beverages (milk, diet soda, and water)	1 L sucrose-sweetened regular cola/d (1800 kJ)	1 L semiskim milk/d (1900 kJ) or still mineral water (0 kJ) or aspartame-sweetened diet cola (15 kJ)

¹HFCS, high-fructose corn syrup.