Table 1.
Estimates of false discovery rate
| Analysis | SI | SII | SIII | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
|
(trait) |
LOD-d |
1% |
5% |
10% |
1% |
5% |
10% |
1% |
5% |
10% |
| MIM |
1.0 |
9.1 |
9.1 |
9.9 |
8.9 |
9.2 |
10.0 |
7.2 |
7.9 |
8.7 |
| (T1) |
1.5 |
3.9 |
4.4 |
5.3 |
3.7 |
4.3 |
5.3 |
2.8 |
3.5 |
4.1 |
| |
2.0 |
2.0 |
2.7 |
3.6 |
1.8 |
2.2 |
3.0 |
1.4 |
1.9 |
2.3 |
| MIM |
1.0 |
8.0 |
8.7 |
8.9 |
7.9 |
8.6 |
9.6 |
6.2 |
7.0 |
7.8 |
| (T2) |
1.5 |
3.9 |
4.2 |
4.7 |
3.2 |
4.1 |
5.4 |
3.1 |
3.7 |
4.5 |
| |
2.0 |
2.0 |
2.3 |
3.0 |
1.2 |
2.2 |
3.6 |
1.2 |
2.1 |
2.8 |
| MIM |
1.0 |
10.7 |
9.6 |
9.9 |
12.4 |
13.8 |
18.0 |
– |
– |
– |
| (T3) |
1.5 |
3.8 |
4.2 |
4.9 |
7.5 |
9.0 |
11.4 |
– |
– |
– |
| |
2.0 |
1.8 |
2.3 |
3.1 |
4.8 |
6.5 |
8.5 |
– |
– |
– |
| MTMIM |
1.0 |
4.6 |
5.4 |
6.9 |
8.5 |
9.2 |
10.0 |
5.6 |
7.8 |
8.4 |
| |
1.5 |
1.9 |
2.7 |
4.0 |
3.3 |
4.1 |
4.9 |
2.9 |
5.2 |
5.7 |
| 2.0 | 1.1 | 1.9 | 3.3 | 1.4 | 2.4 | 3.2 | 2.2 | 4.1 | 4.5 | |
Estimates of FDR (%) in the MIM and MTMIM models as observed in scenarios SI, SII and SIII across genome-wide significance levels (1, 5 and 10%) and LOD-d support intervals.