Table 2.
Clinical outcomes of women and men stratified by abciximab administration strategy
Variable | Early abciximab | Late abciximab | OR (95 % CI) | p value | Adjusted OR (95 % CI) | p value |
---|---|---|---|---|---|---|
Women | n = 186 | n = 86 | ||||
30 day | ||||||
Death | 4.8 % | 14.0 % | 0.31 (0.13–0.78) | 0.023 | 0.26 (0.10–0.69) | 0.007 |
Death + nonfatal reinfarction | 6.5 % | 16.3 % | 0.36 (0.16–0.80) | 0.013 | 0.29 (0.12–0.69) | 0.005 |
Death + nonfatal reinfarction + urgent revascularization | 7.5 % | 17.4 % | 0.39 (0.18–0.84) | 0.016 | 0.32 (0.14–0.74) | 0.007 |
Major bleeding requiring transfusion | 5.4 % | 2.3 % | 2.39 (0.51–11.13) | 0.27 | 2.22 (0.47–10.57) | 0.32 |
Intracranial haemorrhage | 0 % | 0 % | – | – | – | – |
Puncture site haematoma | 12.9 % | 9.3 % | 1.44 (0.62–3.36) | 0.39 | 1.21 (0.51–2.88) | 0.67 |
All bleeding | 16.7 % | 11.6 % | 1.52 (0.71–3.26) | 0.28 | 1.30 (0.60–2.85) | 0.51 |
1 year | ||||||
Death | 7.5 % | 17.4 % | 0.39 (0.18–0.84) | 0.016 | 0.37 (0.16–0.84) | 0.017 |
Men | n = 541 | n = 273 | ||||
30 day | ||||||
Death | 3.7 % | 5.5 % | 0.66 (0.33–1.31) | 0.24 | 0.69 (0.35–1.39) | 0.27 |
Death + nonfatal reinfarction | 4.6 % | 7.0 % | 0.65 (0.35–1.20) | 0.17 | 0.68 (0.37–1.28) | 0.23 |
Death + nonfatal reinfarction + urgent revascularization | 5.0 % | 8.1 % | 0.60 (0.34–1.07) | 0.09 | 0.64 (0.36–1.17) | 0.15 |
Major bleeding requiring transfusion | 1.3 % | 1.1 % | 1.18 (0.30–4.60) | 0.81 | 1.40 (0.35–5.64) | 0.64 |
Intracranial haemorrhage | 0 % | 0 % | – | – | – | – |
Puncture site haematoma | 6.7 % | 7.3 % | 0.90 (0.51–1.59) | 0.72 | 0.94 (0.53–1.68) | 0.83 |
All bleeding | 7.6 % | 8.1 % | 0.94 (0.55–1.61) | 0.81 | 0.98 (0.57–1.71) | 0.95 |
1 year | ||||||
Death | 5.2 % | 8.1 % | 0.62 (0.35–1.11) | 0.11 | 0.68 (0.38–1.22) | 0.19 |
Values are presented as percentages and unadjusted and adjusted for propensity score odds ratios (OR) with 95 % confidence intervals (CI)