Table 2.

Adjusted^a Odds Ratios for First-Course Treatment Type Among Adolescent and Young adult Females 15–39 Years of Age with In Situ and Stages I–III Breast Cancer^b by Select Demographic and Tumor Characteristics, California 1992–2009

	Surgery/Radiationc (versus BCS with radiation)		Chemotherapy (versus none)
	BCS without radiation	Mastectomyd	Given
Age at diagnosis (years)	0.99 (0.97–1.00)	0.99 (0.98–1.00)	0.97 (0.96–0.99)
Race/ethnicity
White	Ref	Ref	Ref
Black	1.25 (1.05–1.49)	0.92 (0.81–1.05)	0.98 (0.84–1.13)
Hispanic	1.13 (1.00–1.28)	1.11 (1.01–1.21)	1.14 (1.03–1.26)
Asian/Pacific Islander	0.93 (0.80–1.08)	1.30 (1.18–1.44)	0.92 (0.82–1.03)
Other/unknown	3.33 (2.00–5.55)	1.79 (1.13–2.85)	0.96 (0.61–1.49)
Year of diagnosis
1992–1993	Ref	Ref	Ref
1994–1995	1.08 (0.85–1.36)	0.85 (0.74–0.97)	1.01 (0.86–1.18)
1996–1997	1.51 (1.20–1.88)	0.80 (0.70–0.92)	1.04 (0.88–1.22)
1998–1999	1.76 (1.41–2.20)	0.77 (0.67–0.88)	1.02 (0.86–1.19)
2000–2001	2.27 (1.83–2.82)	0.85 (0.74–0.98)	1.06 (0.90–1.24)
2002–2003	2.36 (1.90–2.95)	0.79 (0.68–0.91)	1.05 (0.89–1.23)
2004–2005	1.77 (1.41–2.22)	0.66 (0.58–0.77)	0.95 (0.80–1.12)
2006–2007	2.40 (1.91–3.00)	0.79 (0.69–0.92)	0.93 (0.79–1.10)
2008–2009	3.52 (2.80–4.43)	1.22 (1.05–1.42)	0.75 (0.64–0.88)
AJCC stage at diagnosis
In situ	2.19 (1.86–2.58)	1.84 (1.62–2.10)	0.01 (0.01–0.02)
I	Ref	Ref	Ref
II	1.29 (1.15–1.44)	2.16 (2.00–2.34)	4.00 (3.69–4.34)
III	1.09 (0.86–1.38)	6.68 (5.80–7.68)	7.03 (6.02–8.21)
Tumor grade
Low	Ref	Ref	Ref
High	1.10 (0.98–1.23)	1.10 (1.02–1.19)	1.58 (1.45–1.72)
Unknown	1.53 (1.29–1.81)	1.16 (1.02–1.32)	0.59 (0.52–0.68)
Hormone receptor status
Positive or borderline	Ref	Ref	Ref
Negative	0.95 (0.84–1.07)	1.18 (1.08–1.28)	0.78 (0.71–0.86)
Unknown	2.00 (1.71–2.34)	1.48 (1.32–1.66)	0.32 (0.28–0.37)
Neighborhood SES quintile
Highest	Ref	Ref	Ref
Higher-middle	0.99 (0.86–1.13)	0.88 (0.80–0.97)	1.04 (0.93–1.16)
Middle	1.09 (0.94–1.26)	0.98 (0.89–1.09)	1.02 (0.91–1.15)
Lower-middle	1.20 (1.03–1.40)	1.09 (0.98–1.22)	0.88 (0.78–0.99)
Lowest	1.24 (1.04–1.47)	1.10 (0.97–1.24)	0.77 (0.67–0.88)
National Cancer Institute-–designated hospital
No	Ref	Ref	Ref
Yes	0.90 (0.75–1.07)	0.85 (0.75–0.97)	1.53 (1.30–1.80)

Note: p<0.05 indicated in bold.

^aAdjusted for all variables in table.

^bModels include 19,035 patients.

^cOdds ratios for the “no surgery” treatment category are not presented as this group comprised a very small portion (n=313, 1.6%) of the study population.

^dIncluding mastectomy with radiation and mastectomy without radiation.

AJCC, American Joint Committee on Cancer; BCS, breast-conserving surgery; Ref, reference; SES, socioeconomic status.