Table 4.

Significant predictors of local control and overall survival on univariate and multivariate analyses

Overall Survival			Local Control
Factor	Univariate	Multivariate	Factor	Univariate	Multivariate
Systemic therapy post-SBRT	P = .0209	P = .0246/HR = 2.338 (95% CI, 1.115–4.903)	18–26 Gy/1–2 fractions vs 18–40 Gy/3–5 fractions	P = .0292	P = .0224;/HR = 0.322 (95% CI, 0.122–0.852)
Preoperative Bilsky grade	P = .0956	NS	Postoperative Bilsky grade 0/1 vs 2/3	P = .0092	P = .003;/HR = 0.225 (95% CI, 0.084–0.604)
18–26 Gy in 1–2 fractions vs 18–40 Gy in 3–5 fractions	P = .09	NS	CTV V80	P = .0914	NS
Presence of lung and liver metastases	P = .0715	NS	Systemic therapy post-SBRT	P = .1012	NS

Abbreviations: NS, not significant; CTV V80, volume of the clinical target volume encompassed by 80% of the prescribed dose.

Only those factors with P≤ .1 are shown for the univariate analysis and only those significant at P≤ .05 are shown for the multivariate analysis.