Figure 4. Immunofluorescence localization of Izumo 1 and Izumo 3 on sperm.
Acrosome-intact or acrosome-reacted sperm were fixed, permeabilized and incubated with antibodies 2417 or 3149 against Izumo 1 or antibodies against Izumo 3. I: immune sera, PI: pre-immune sera. The percentage of acrosome reaction was 77–81%.