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. Author manuscript; available in PMC: 2013 Sep 20.
Published in final edited form as: Mol Reprod Dev. 2009 Dec;76(12):1188–1199. doi: 10.1002/mrd.21092

Figure 9.

Figure 9

A: Summary of the results on complex formation for the recombinant proteins. The second construct differs from the top one by the presence of the histidine tag (shown as a short hook) in the C-terminal end. The numbers indicate the aminoacid residues marking the boundaries of the different domains. B: Proposed model for the formation of multimers for Izumo 1 and Izumo 3. Dimers of Izumo 1 and Izumo 3 are stabilized by interactions in the Izumo domain. Formation of Izumo 1 multimers of higher order is proposed to be mediated by the interaction of the cytoplasmic tails and/or the transmembrane domains.