Table 4.
IK1 time-dependent decay during depolarizing steps from different Vh
| Vh (mV) | Param | VM cells | P cells |
|---|---|---|---|
| −80 | Measured at (mV) | −58.8 ± 0.7 | −59.6 ± 6.4 |
| IK1 decay (pA) | 317 ± 29 (18/18) | 237 ± 24* (18/18) | |
| τ (msec) | 6.3 ± 0.9 | 5.9 ± 1.2 | |
| −70 | Measured at (mV) | −55.6 ± 1.2 | −59.3 ± 0.6* |
| IK1 decay (pA) | 226 ± 3.7 (16/16) | 62.9 ± 16.5* (11/16) | |
| −60 | Measured at (mV) | −50.0 ± 0.0 | −50.0 ± 0.0 |
| IK1 decay (pA) | 78.4 ± 26.2 (6/15) | 21.1 ± 18.2 (2/15) | |
| −50 | Measured at (mV) | −40.0 ± 0.0 | −40.0 ± 0.0 |
| IK1 decay (pA) | 24.1 ± 15.6 (4/16) | 12.8 ± 8.8 (2/16) |
Measured at (mV), voltage in mV at which the decay of IK1 was measured; IK1 decay (pA), amplitude of IK1 time-dependent decay at beginning of step; τ (msec), time constant of IK1 exponential decay; Vh (mV), holding potential in mV; VM cells, data from ventricular myocardial cells; P cells, data from Purkinje cells; Numbers in parenthesis (e.g., 18/18), number of cells in which IK1 decay was present over the total number of cells studied; *statistically significant difference between P and VM cells data.