Table 6. Methylation status in histopathologically benign and matched prostate tumor specimens in 58 cases.
| Specimen | ||
|---|---|---|
|
|
||
| Benign | Tumor | |
| No. race (%): | ||
| White | 31 (54) | — |
| Black | 27 (47) | — |
| Cohort entry: | ||
| Mean ± SD cohort entry age | 60.2 ± 6.1 | 3.6 ± 2.0 |
| Median cohort entry date | 9/7/94 | 4/27/99 |
| Mean ± SD PSA cohort entry-diagnosis (ng/ml) | 7.7 ± 4.6 | 14.2 ± 12.9 |
| % Tumor stage: | — | |
| 2A | 26 | |
| 2B | 40 | |
| 2C | 19 | |
| 3A | 9 | |
| 3B | 5 | |
| 3C | 2 | |
| % Gleason grade: | — | |
| 6 or Less | 47 | |
| 7 (3 + 4) | 14 | |
| 7 (4 + 3) | 12 | |
| 8–10 | 28 | |
| % Pos methylation (No. pts): | ||
| MGMT (53) | 13 | 6 |
| APC (52) | 31 | 77 |
| RARB (54) | 30 | 61 |
| CCND2 (49) | 4 | 39 |
| RASSF1 (44) | 30 | 48 |