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. Author manuscript; available in PMC: 2014 Mar 4.
Published in final edited form as: Neuron. 2013 Sep 4;79(5):903–916. doi: 10.1016/j.neuron.2013.06.035

Figure 4. DAF-21/Hsp90 Interacts with EBAX-1 and Regulates AVM Guidance.

Figure 4

(A) Interactions between DAF-21 and the EBAX-1 WT or truncated mutants in Y2H assays. + and ++, intermediate and strong interaction; –, no interaction.

(B) Genetic effects of daf-21 and ebax-1 mutants on AVM guidance.

(C) Rescue analyses of daf-21 and ebax-1 transgenes in double and triple mutants. EBAX-1 (+) and DAF-21 (+), overexpression of Pebax-1::EBAX-1 WT and Pdaf-21::DAF-21 WT in indicated mutant backgrounds. Data in (B) and (C) represent means ± SEM. *p<0.05, **p<0.01, and ***p<0.001 relative to the unc-6 single mutant; #p<0.05, ##p<0.01, and ###p<0.001 relative to indicated controls; one-way ANOVA.