Table 4. Summary of effects of group membership on ROI parameters in the Full and Matched sample.
Full Sample | ||||||||||
ROI | Parameter | Beta | T value | P value | Lower CL | Upper CL | Degrees Freedom | # NT | # ASD | Baye's Factor |
RTPJ | Mean T | 0.101 | 1.030 | 0.885 | −0.153 | 0.356 | 455 | 436 | 28 | 4.048 |
# Voxels | 17.160 | 1.679 | 0.447 | −9.276 | 43.595 | 455 | 436 | 28 | 1.778 | |
X Center | 0.463 | 0.757 | 0.972 | −1.120 | 2.047 | 455 | 436 | 28 | 5.090 | |
Y Center | 0.207 | 0.316 | 1.000 | −1.488 | 1.903 | 455 | 436 | 28 | 6.353 | |
Z Center | −1.001 | −1.317 | 0.715 | −2.967 | 0.965 | 455 | 436 | 28 | 2.955 | |
Found | 0.300 | 0.818 | 0.960 | −0.649 | 1.249 | 484 | 462 | 31 | 5.089 | |
LTPJ | Mean T | 0.073 | 0.723 | 0.978 | −0.189 | 0.335 | 422 | 407 | 24 | 4.872 |
# Voxels | 12.161 | 1.272 | 0.746 | −12.575 | 36.897 | 422 | 407 | 24 | 2.930 | |
X Center | 1.091 | 1.494 | 0.584 | −0.799 | 2.980 | 422 | 407 | 24 | 2.204 | |
Y Center | −0.128 | −0.191 | 1.000 | −1.867 | 1.611 | 422 | 407 | 24 | 6.107 | |
Z Center | 0.621 | 0.813 | 0.961 | −1.355 | 2.596 | 422 | 407 | 24 | 4.569 | |
Found | 0.298 | 1.118 | 0.841 | −0.391 | 0.987 | 484 | 462 | 31 | 3.872 | |
PC | Mean T | 0.025 | 0.255 | 1.000 | −0.226 | 0.276 | 437 | 418 | 28 | 6.450 |
# Voxels | 2.874 | 0.270 | 1.000 | −24.654 | 30.401 | 437 | 418 | 28 | 6.426 | |
X Center | 0.128 | 0.255 | 1.000 | −1.175 | 1.432 | 437 | 418 | 28 | 6.450 | |
Y Center | −0.523 | −0.852 | 0.951 | −2.109 | 1.064 | 437 | 418 | 28 | 4.731 | |
Z Center | 0.965 | 1.053 | 0.875 | −1.407 | 3.338 | 437 | 418 | 28 | 3.956 | |
Found | −0.065 | −0.188 | 1.000 | −0.956 | 0.826 | 484 | 462 | 31 | 6.859 | |
DMPFC | Mean T | 0.097 | 1.371 | 0.675 | −0.086 | 0.281 | 328 | 316 | 21 | 2.453 |
# Voxels | 6.730 | 0.871 | 0.945 | −13.291 | 26.752 | 328 | 316 | 21 | 4.106 | |
X Center | 0.116 | 0.126 | 1.000 | −2.277 | 2.509 | 328 | 316 | 21 | 5.779 | |
Y Center | 0.096 | 0.167 | 1.000 | −1.394 | 1.586 | 328 | 316 | 21 | 5.747 | |
Z Center | −0.982 | −1.430 | 0.633 | −2.762 | 0.797 | 328 | 316 | 21 | 2.272 | |
Found | −0.092 | −0.418 | 0.999 | −0.658 | 0.475 | 484 | 462 | 31 | 6.423 | |
MMPFC | Mean T | 0.120 | 1.509 | 0.572 | −0.086 | 0.327 | 308 | 299 | 18 | 1.931 |
# Voxels | 13.463 | 1.504 | 0.578 | −9.745 | 36.672 | 308 | 299 | 18 | 1.945 | |
X Center | −0.140 | −0.172 | 1.000 | −2.255 | 1.975 | 308 | 299 | 18 | 5.368 | |
Y Center | −0.112 | −0.170 | 1.000 | −1.830 | 1.605 | 308 | 299 | 18 | 5.369 | |
Z Center | 0.117 | 0.175 | 1.000 | −1.612 | 1.845 | 308 | 299 | 18 | 5.365 | |
Found | 0.084 | 0.398 | 0.999 | −0.460 | 0.627 | 484 | 462 | 31 | 6.473 | |
VMPFC | Mean T | 0.148 | 2.056 | 0.222 | −0.039 | 0.335 | 260 | 251 | 18 | 0.794 |
# Voxels | 13.533 | 1.643 | 0.476 | −7.840 | 34.905 | 260 | 251 | 18 | 1.588 | |
X Center | −0.308 | −0.707 | 0.980 | −1.440 | 0.823 | 260 | 251 | 18 | 4.313 | |
Y Center | −0.056 | −0.085 | 1.000 | −1.749 | 1.638 | 260 | 251 | 18 | 5.396 | |
Z Center | −0.651 | −0.959 | 0.916 | −2.414 | 1.111 | 260 | 251 | 18 | 3.564 | |
Found | −0.032 | −0.157 | 1.000 | −0.566 | 0.502 | 484 | 462 | 31 | 6.894 | |
RSTS | Mean T | 0.064 | 0.851 | 0.951 | −0.130 | 0.257 | 410 | 397 | 22 | 4.277 |
# Voxels | 7.437 | 0.941 | 0.922 | −13.009 | 27.883 | 410 | 397 | 22 | 3.969 | |
X Center | −0.535 | −0.688 | 0.983 | −2.548 | 1.478 | 410 | 397 | 22 | 4.802 | |
Y Center | 2.894 | 1.433 | 0.631 | −2.333 | 8.121 | 410 | 397 | 22 | 2.316 | |
Z Center | −1.609 | −1.217 | 0.782 | −5.030 | 1.812 | 410 | 397 | 22 | 3.014 | |
Found | 0.476 | 1.977 | 0.256 | −0.147 | 1.099 | 484 | 462 | 31 | 1.108 | |
Matched Sample | ||||||||||
ROI | Parameter | Beta | T value | P value | Lower CL | Upper CL | Degrees Freedom | # NT | # ASD | Baye's Factor |
RTPJ | Mean T | 0.098 | 0.842 | 0.955 | −0.215 | 0.412 | 44 | 26 | 26 | 3.511 |
# Voxels | 2.261 | 0.194 | 1.000 | −29.165 | 33.687 | 44 | 26 | 26 | 4.746 | |
X Center | 0.335 | 0.348 | 1.000 | −2.257 | 2.927 | 44 | 26 | 26 | 4.570 | |
Y Center | 0.878 | 0.917 | 0.934 | −1.700 | 3.456 | 44 | 26 | 26 | 3.310 | |
Z Center | −0.906 | −0.939 | 0.927 | −3.502 | 1.691 | 44 | 26 | 26 | 3.251 | |
Found | −0.282 | −0.346 | 1.000 | −2.469 | 1.906 | 46 | 27 | 27 | 4.650 | |
LTPJ | Mean T | 0.036 | 0.312 | 1.000 | −0.281 | 0.354 | 38 | 24 | 22 | 4.375 |
# Voxels | −2.482 | −0.232 | 1.000 | −31.513 | 26.549 | 38 | 24 | 22 | 4.461 | |
X Center | 1.391 | 1.318 | 0.728 | −1.470 | 4.252 | 38 | 24 | 22 | 2.129 | |
Y Center | 0.328 | 0.349 | 1.000 | −2.219 | 2.875 | 38 | 24 | 22 | 4.327 | |
Z Center | −0.754 | −0.723 | 0.979 | −3.585 | 2.077 | 38 | 24 | 22 | 3.623 | |
Found | 0.220 | 0.498 | 0.997 | −0.968 | 1.409 | 46 | 27 | 27 | 4.387 | |
PC | Mean T | 0.073 | 0.500 | 0.997 | −0.322 | 0.469 | 39 | 22 | 25 | 4.121 |
# Voxels | −1.212 | −0.080 | 1.000 | −42.268 | 39.843 | 39 | 22 | 25 | 4.595 | |
X Center | 0.942 | 1.351 | 0.707 | −0.946 | 2.831 | 39 | 22 | 25 | 2.064 | |
Y Center | −0.198 | −0.238 | 1.000 | −2.459 | 2.062 | 39 | 22 | 25 | 4.493 | |
Z Center | 0.293 | 0.201 | 1.000 | −3.646 | 4.232 | 39 | 22 | 25 | 4.525 | |
Found | −1.348 | −2.000 | 0.246 | −3.159 | 0.463 | 46 | 27 | 27 | 0.849 | |
DMPFC | Mean T | 0.113 | 1.194 | 0.809 | −0.146 | 0.372 | 31 | 20 | 19 | 2.294 |
# Voxels | 14.279 | 1.022 | 0.896 | −24.041 | 52.598 | 31 | 20 | 19 | 2.701 | |
X Center | 0.346 | 0.341 | 1.000 | −2.439 | 3.131 | 31 | 20 | 19 | 4.044 | |
Y Center | −0.086 | −0.107 | 1.000 | −2.280 | 2.108 | 31 | 20 | 19 | 4.235 | |
Z Center | −0.994 | −1.065 | 0.877 | −3.554 | 1.566 | 31 | 20 | 19 | 1.949 | |
Found | −0.002 | −0.005 | 1.000 | −0.900 | 0.897 | 46 | 27 | 27 | 4.908 | |
MMPFC | Mean T | 0.141 | 1.685 | 0.493 | −0.096 | 0.378 | 21 | 13 | 16 | 1.171 |
# Voxels | 14.182 | 1.201 | 0.812 | −19.258 | 47.621 | 21 | 13 | 16 | 2.049 | |
X Center | 0.641 | 0.483 | 0.998 | −3.120 | 4.403 | 21 | 13 | 16 | 3.389 | |
Y Center | 0.067 | 0.068 | 1.000 | −2.736 | 2.871 | 21 | 13 | 16 | 3.735 | |
Z Center | −0.549 | −0.487 | 0.997 | −3.738 | 2.641 | 21 | 13 | 16 | 3.383 | |
Found | −0.180 | −0.617 | 0.990 | −0.964 | 0.604 | 46 | 27 | 27 | 4.134 | |
VMPFC | Mean T | 0.145 | 1.659 | 0.500 | −0.097 | 0.386 | 27 | 19 | 16 | 1.272 |
# Voxels | 14.575 | 1.530 | 0.590 | −11.818 | 40.967 | 27 | 19 | 16 | 1.506 | |
X Center | −1.045 | −1.712 | 0.461 | −2.737 | 0.647 | 27 | 19 | 16 | 1.184 | |
Y Center | −0.392 | −0.361 | 1.000 | −3.396 | 2.613 | 27 | 19 | 16 | 3.830 | |
Z Center | −0.994 | −1.029 | 0.894 | −3.671 | 1.682 | 27 | 19 | 16 | 2.571 | |
Found | 0.241 | 0.733 | 0.976 | −0.641 | 1.122 | 46 | 27 | 27 | 3.851 | |
RSTS | Mean T | 0.036 | 0.513 | 0.997 | −0.155 | 0.227 | 37 | 25 | 20 | 4.007 |
# Voxels | 0.590 | 0.063 | 1.000 | −24.973 | 26.154 | 37 | 25 | 20 | 4.497 | |
X Center | 0.182 | 0.165 | 1.000 | −2.818 | 3.182 | 37 | 25 | 20 | 4.451 | |
Y Center | 1.453 | 0.530 | 0.996 | −5.985 | 8.890 | 37 | 25 | 20 | 3.976 | |
Z Center | −0.564 | −0.311 | 1.000 | −5.493 | 4.365 | 37 | 25 | 20 | 4.316 | |
Found | 0.740 | 1.556 | 0.536 | −0.538 | 2.017 | 46 | 27 | 27 | 1.675 |
For each ROI/parameter pair, the effect of group membership was measured via a GLM. The estimated beta value, the t− and p- values, the 99% confidence intervals, and the number of NT and ASD individuals included in the regression are reported. Also reported is the Baye’s factor, which relates the odds ratio of the null hypothesis (group membership has no effect) to the alternate hypothesis.