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. 2013 Sep 20;8(9):e76790. doi: 10.1371/journal.pone.0076790

Figure 5. Inhibition of ERK1/2 by U0126 increased the levels of proinflammatory cytokines in plasma.

Figure 5

Mice were pretreated with U0126 or vehicle and then subjected to one hour ischemia followed by 6 hours reperfusion in the intestine (n=5). The relatively levels of cytokines in plasma was determined using a commercial kit. A. The relatively level of cytokines TNF-α in plasma. B. The relatively level of cytokines IL-6 in plasma. C. The relatively level of cytokines IL-1β in plasma. Sham-U=Sham-U0126, IR=I/R, IR-U=I/R-U0126.