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. 2013 Sep 20;8(9):e75139. doi: 10.1371/journal.pone.0075139

Figure 3. Resveratrol inhibited T cell activation by enhancing the expression of Sirt1.

Figure 3

(a) The expression of Sirt1 in resveratrol treated (R), anti-CD3/CD28 antibody-activated (A), and naïve T cells (N) cells were detected through Western blot. GAPDH was used as loading reference. (b) The expression of Sirt1 in wild-type T cells (N), resveratrol-treated T cells (R), and mir-34a TG mouse T cells (34a). GAPDH was used as loading reference. (c, d) The proliferation of CD4+ T cells from wild-type mice and mir-34a TG mice, some of which were treated with resveratrol (**P < 0.01). The data are representative of three time-independent repetitions.