Table 1.
Patient | Age/gender | Habitual seizure semiology | MRI | Interictal EEG | Presumed focus |
---|---|---|---|---|---|
1 | 25/F | Epigastric aura, out-of-breath sensation, LOC | RTP nodular heterotopia, abnormal overlying cortex | RFT spike-and-waves | RTP lesion |
2 | 39/M | Flashing lights in L visual field, sometimes L eye deviation, LOC | RTO nodular heterotopia, abnormal overlying cortex | R posterior spikes and spike-and-waves | RTO lesion |
3 | 52/M | Visual and auditory distortions with language impairment | Bil nodular heterotopia, L anterior T resection | Independent LT and RT spikes | BilTO lesions |
4 | 23/M | Aura of déjà-vu, then LOC and motor automatisms | Bil nodular heterotopia | Independent LT and RT spikes | BilTO lesions |
5 | 20/F | Visual distortions with change of colors, confusion | RTPO nodular heterotopia, abnormal overlying cortex | RTP spikes/sharp waves | RTPO lesion |
6 | 11/M | Aura of fear, screaming, L head deviation | RF focal cortical dysplasia | RF spike-and-waves | RF lesion |
7 | 33/M | Somatosensory sensation in R elbow, non-tonic R arm elevation | LCP focal cortical dysplasia | LCP polyspikes | LCP lesion |
8 | 26/M | Chest pressure feeling, LOC, staring, chewing, sometimes R eye deviation | Band heterotopia TPO, predominantly R | BilTO spike and slow waves with R predominance | RTPO lesion |
9 | 23/F | Visual illusions, micropsia, blindness, or lights forming faces | Band heterotopia predominantly BilFPO | Synchronous and rhythmic sharp and slow wave discharges over posterior regions | BilO lesion |
10 | 68/M | L eyelid clonus, jerks of all 4 limbs | Metastasis, R posterior SMA | RF slow waves | RC lesion |
11 | 42/M | Nocturnal slow head/chest flexion, left arm extension, right head deviation | RF atrophy | RFC slow waves | RF lesion |
12 | 36/M | Either drop attacks or L head and eye deviation and L arm dystonic posturing | LFT atrophy | Generalized slow waves, R polysharp-slow waves, maximum over RFT region | FT, earlier R involvement |
13 | 28/F | Aura of déjà-vu, anxiety, palpitations, dysphasia, staring | Normal | L slowing, LT spikes | L mesial T |
14 | 22/F | GTCs or absences with staring and unresponsiveness | Normal | BilF sharp and slow waves during sleep, LT spikes, Bil fast activity predominantly L | BilF predominantly L |
15 | 19/F | L visual field distortions (sometimes also R), LOC, L eye deviation, tongue movements | Normal | RTPO spikes | RTPO |
Abbreviations: LOC: loss of consciousness, GTC: generalized tonic-clonic seizures, R: right, L: left, Bil: bilateral, F: frontal, C: central, T: temporal, P: parietal, O: occipital, SMA: supplementary motor area.