Table 3.

Locations of activations and deactivations identified by the ICA method.

Patient	Presumed focus	# seizure-related ICA components with a clear peak	ICA fMRI activation	ICA fMRI deactivation	Earliest activation
1	RTP lesion	39	Widespread RFTP, L cerebellum	BilO, scattered LFTP, R cerebellum	RFT
2	RTO lesion	5	Mesial F	BilF	Mesial F
3	BilTO lesions	0	None	None	None
4	BilTO lesions	35	BilT, BilTO, Bil cerebellum	BilFT, BilO	Brainstem
5	RTPO lesion	3	RTPO (around the lesion)	None	Cortex overlying lesion
6	RF lesion	27	RF, RT, Bil cerebellum	BilF, RT, BilPO	RF
7	LCP lesion	12	BilTO, LCP, Bil cerebellum	RF, BilF, RCP	BilO
8	RTPO lesion	14	RTO, RF, RP, LF	LFP, BilF, BilO	RTO
9	BilO lesion	1	None	RO	None
10	RC lesion	6	BilCP, RTO, LO, Bil cerebellum	LF, BilT	BilO
11	RF lesion	12	BilF, BilTP	BilF	BilF
12	FT, earlier R involvement	2	RFT	RF, RPO, L cerebellum	RFT
13	L mesial T	69	Widespread L hemisphere, BilTP, Bil cerebellum	RFT, BilO, BilC, Bil cerebellum	LF
14	BilF predominantly L	25	BilFT, Bil cerebellum	BilTP, BilO, Bil cerebellum	BilFT
15	RTPO	1	RP	None	RP

The location of the presumed epileptogenic focus is repeated from Table 1 to facilitate comparisons; concordant responses are indicated in bold type. The last column shows the location of the earliest activation, as determined by the analysis of the HRF peak delays. Abbreviations: R: right, L: left, Bil: bilateral, F: frontal, C: central, T: temporal, P: parietal, O: occipital.